Acacia Pharma initiates two pivotal Stage 3 research of APD421 in prevention of PONV Acacia Pharma, a pharmaceutical company specialising in the advancement of medications for supportive care, announces the initiation of two pivotal Phase 3 studies of APD421 in preventing post-operative nausea & vomiting . PONV continues to be a clinically significant problem in patients undergoing major surgery, despite the option of a variety of anti-emetic medications levitra precio . The Phase 3 research are taking place in 19 main centres in France, Germany and the united states. They will recruit a complete of 680 surgical patients at moderate to risky of suffering PONV . The trials compare the optimal dose of APD421 against placebo, the principal endpoint being no vomiting or retching and no requirement of anti-emetic rescue medicine in the first 24 hours after surgery.
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