Recent data shows at the 2008 American Society of Clinical Oncologists , colorectal cancer patients presented with tumors, K-Ras oncogene mutations did not respond on EGFR – inhibitors, such as cetuximab. It is estimated that up to 45 percent of patients with colorectal cancer, these K – Ras gene is mutated. Announcedtherapy http://clobetasocream.com . Characterized K-Ras mutant patient population, Nektar will initiate prospective study to evaluate the efficacy of NKTR-102 monotherapy in these patients. The primary endpoint of this randomized trial clinically meaningful improvement in clinically meaningful improvement in progression-free survival as compared to standard irinotecan monotherapy.
Nectar PEGylation technology, the properties of drugs by increasing drug circulation time in the bloodstream, decreasing immunogenicity and dosing frequency, increasing the bioavailability and the improvement of drug solubility and stability improved. Used to used to modify pharmaceutical agents to preferentially certain systems within the body is targeted. It is a technique that are fixed at the non – toxic polyethylene glycol polymers for therapeutic agents, and it is for most of the major classes of compounds, including proteins, peptides, antibody fragments, small molecules and other drugs. Nektar is also used in eight additional approved partner products in the U.S. Or Europe today, including UCB’s Cimzia for Crohn’s disease, Roche PEGASYS for hepatitis C and Amgen’s Neulasta for neutropenia.
Policy urges Doctors & Dentists to stay alert for signs of Elder Abuse.
Dr. Stephanie Bown, MPS Director of Communications and policy, a sign ‘Elder Report Abuse can take various forms; physical and fiscal Abuse to has probably the most frequent, but abuse may be and mental or sexual.