Rheumatoid arthritis is a progressive autoimmune the characterized by inflammation of the membrane lining in the joints throughout the body. This causes inflammation of the joint and impaired function with pain, stiffness and swelling, ultimately accompanied to irreversible joint destruction and disability click to follow . In addition, the systemic symptoms of RA include fatigue, anemia, osteoporosis, and can affect a shorter life expectancy due to major organ systems and contribute. Unfortunately, after 10 years, fewer than 50 percent of patients are to continue to work or function normally on a daily basis.
About ActemraActemra is the result of research collaboration by Chugai and is being developed globally with Chugai. Actemra is the first humanized interleukin – 6 receptor monoclonal antibody. An extensive clinical development program of five Phase III trials was designed to evaluate clinical findings of Actemra. Four studies are completed and have met their primary endpoints. A fifth study, called a two-year study LITHE , is currently underway and is expected to report the preliminary first-year data in 2008. Actemra is awaiting approval in the U.S. And Europe. Actemra in Japan by Chugai therapy 2005 as a therapy for Castleman ‘s disease into being in April 2008, additional indications for rheumatoid arthritis, juvenile idiopathic arthritis and systemic-onset juvenile idiopathic arthritis were Japan Japan.
– it is a struggle to recent events to remember, While it is easy to remember what happened in the past – it’s hard discussions conversations and TV programs – forgetting regular basis the names from friends or everyday objects – to impotence recall things is one seen or read – difficulty in producing judgments – Repeat the in discussions or lose the thread of which they have to say – you having trouble thinking and argumentation – scared and depressed or angry about their forgetfulness – Do you think other men in their forgetfulness start a comment.
However, to two thirds of people with dementia never been received a diagnosis , either because they does not recognize the symptoms or log in their GP. And for those that who do, it takes an average of almost three years for diagnostic from first develop symptoms denied people having early dementia and proportionate care and support.